Description : Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; functions as a chaperone under ATP-depleted oxidative stress conditions; subunit of GET complex, involved in ATP dependent Golgi to ER trafficking and insertion of tail-anchored (TA) proteins into ER membrane under non-stress conditions; binds as dimer to transmembrane domain (TMD) cargo, shielding TMDs from aqueous solvent; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000002258]

Gene families : OG_03_0002568 (OF) Phylogenetic Tree(s): OG0002568_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YDL100C
Cluster HCCA: Cluster_55

Target Alias Description ECC score Gene Family Method Actions
AFR98119 No alias ATPase GET3;Anion-transporting ATPase 0.06 OF
CAK44253 No alias Anion-transporting ATPase 0.03 OF
SPAC1142.06.1 No alias GET complex ATPase subunit Get3 (predicted)... 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR025723 Anion-transp_ATPase-like_dom 18 335
No external refs found!