Description : Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; functions as a chaperone under ATP-depleted oxidative stress conditions; subunit of GET complex, involved in ATP dependent Golgi to ER trafficking and insertion of tail-anchored (TA) proteins into ER membrane under non-stress conditions; binds as dimer to transmembrane domain (TMD) cargo, shielding TMDs from aqueous solvent; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000002258]
Gene families : OG_03_0002568 (OF) Phylogenetic Tree(s): OG0002568_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDL100C | |
Cluster | HCCA: Cluster_55 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR98119 | No alias | ATPase GET3;Anion-transporting ATPase | 0.06 | OF | |
CAK44253 | No alias | Anion-transporting ATPase | 0.03 | OF | |
SPAC1142.06.1 | No alias | GET complex ATPase subunit Get3 (predicted)... | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR025723 | Anion-transp_ATPase-like_dom | 18 | 335 |
No external refs found! |