Description : Member of an oxysterol-binding protein family with seven members; in S. cerevisiae, family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane and at the nuclear envelope; regulated by sterol binding; OSH2 has a paralog, SWH1, that arose from the whole genome duplication [Source:SGD;Acc:S000002177]
Gene families : OG_03_0001545 (OF) Phylogenetic Tree(s): OG0001545_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDL019C | |
Cluster | HCCA: Cluster_61 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR96881 | No alias | oxysterol-binding protein;PH domain;Oxysterol-binding... | 0.03 | OF | |
AOA66058 | No alias | Pleckstrin homology domain | 0.06 | OF | |
CAG78323 | No alias | Pleckstrin homology domain | 0.09 | OF | |
CAK40942 | No alias | Oxysterol-binding protein | 0.02 | OF | |
CBF82622 | No alias | oxysterol binding protein | 0.04 | OF | |
EAL84646 | No alias | oxysterol binding protein (Osh1), putative | 0.04 | OF | |
EAU87124 | No alias | oxysterol-binding protein | 0.02 | OF | |
EDO03046 | No alias | Pleckstrin homology domain | 0.03 | OF | |
EGR52515 | No alias | Pleckstrin homology domain | 0.03 | OF | |
KHC83569 | No alias | hypothetical protein;PH domain;Oxysterol-binding... | 0.09 | OF | |
MGG_17877T0 | No alias | Putative uncharacterized protein... | 0.03 | OF | |
POW00753 | No alias | Pleckstrin homology domain;Ankyrin repeat-containing... | 0.02 | OF | |
SPBC2F12.05c.1 | No alias | sterol binding ankyrin repeat protein (predicted)... | 0.06 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |