Description : Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Lem3p; CDC50 has a paralog, YNR048W, that arose from the whole genome duplication [Source:SGD;Acc:S000000690]

Gene families : OG_03_0001056 (OF) Phylogenetic Tree(s): OG0001056_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YCR094W
Cluster HCCA: Cluster_13

Target Alias Description ECC score Gene Family Method Actions
EAU88419 No alias transcription regulator 0.02 OF
ESU16706 No alias CDC50/LEM3 family 0.02 OF
KHC73503 No alias hypothetical protein;LEM3 (ligand-effect modulator 3)... 0.02 OF
MGG_12405T0 No alias Cell division control protein 50... 0.02 OF
SPBC1773.11c.1 No alias CDC50 domain protein, implicated in signal transduction... 0.02 OF

Type GO Term Name Evidence Source
CC GO:0016020 membrane IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR005045 CDC50/LEM3_fam 63 359
No external refs found!