Description : Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Lem3p; CDC50 has a paralog, YNR048W, that arose from the whole genome duplication [Source:SGD;Acc:S000000690]
Gene families : OG_03_0001056 (OF) Phylogenetic Tree(s): OG0001056_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YCR094W | |
| Cluster | HCCA: Cluster_13 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| EAU88419 | No alias | transcription regulator | 0.02 | OF | |
| ESU16706 | No alias | CDC50/LEM3 family | 0.02 | OF | |
| KHC73503 | No alias | hypothetical protein;LEM3 (ligand-effect modulator 3)... | 0.02 | OF | |
| MGG_12405T0 | No alias | Cell division control protein 50... | 0.02 | OF | |
| SPBC1773.11c.1 | No alias | CDC50 domain protein, implicated in signal transduction... | 0.02 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| CC | GO:0016020 | membrane | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR005045 | CDC50/LEM3_fam | 63 | 359 |
| No external refs found! |