Description : Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway; ELO2 has a paralog, ELO1, that arose from the whole genome duplication; lethality of the elo2 elo3 double null mutation is functionally complemented by human ELOVL1 and weakly complemented by human ELOVL3 or ELOV7 [Source:SGD;Acc:S000000630]
Gene families : OG_03_0000762 (OF) Phylogenetic Tree(s): OG0000762_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YCR034W | |
| Cluster | HCCA: Cluster_51 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AOA68742 | No alias | ELO family | 0.04 | OF | |
| CAG83378 | No alias | ELO family | 0.02 | OF | |
| CAK37859 | No alias | GNS1/SUR4 family | 0.02 | OF | |
| EAL86028 | No alias | fatty acid elongase (Gns1), putative | 0.02 | OF | |
| EAU93111 | No alias | fatty acid elongase | 0.02 | OF | |
| EGR52556 | No alias | ELO family | 0.03 | OF | |
| KHC81383 | No alias | hypothetical protein;GNS1/SUR4 family | 0.05 | OF | |
| MGG_07280T0 | No alias | Fatty acid elongase [Source:UniProtKB/TrEMBL;Acc:G4MUK6] | 0.04 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| CC | GO:0016021 | integral component of membrane | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR002076 | ELO_fam | 66 | 305 |
| No external refs found! |