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  5. YCL061C

YCL061C


Description : S-phase checkpoint protein required for DNA replication; couples DNA helicase and polymerase; interacts with and stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; defines a novel S-phase checkpoint with Hog1p that coordinates DNA replication and transcription upon osmostress; protects uncapped telomeres; Dia2p-dependent degradation mediates checkpoint recovery; mammalian claspin homolog [Source:SGD;Acc:S000000566]


Gene families : OG_03_0004326 (OF) Phylogenetic Tree(s): OG0004326_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YCL061C
Cluster HCCA: Cluster_37

Target Alias Description ECC score Gene Family Method Actions
AOA66651 No alias DNA replication checkpoint mediator, MRC1 domain 0.17 OF
CAG79996 No alias DNA replication checkpoint mediator, MRC1 domain 0.12 OF
CAK39478 No alias MRC1-like domain 0.09 OF
CBF77232 No alias conserved hypothetical protein 0.15 OF
EAA31731 No alias DNA replication checkpoint mediator, MRC1 domain 0.12 OF
EAL87288 No alias conserved hypothetical protein 0.01 OF
EDO02503 No alias DNA replication checkpoint mediator, MRC1 domain 0.1 OF
EGR47800 No alias DNA replication checkpoint mediator, MRC1 domain 0.12 OF
ESU16584 No alias DNA replication checkpoint mediator, MRC1 domain 0.12 OF
KHC83886 No alias hypothetical protein;MRC1-like domain 0.2 OF
MGG_01813T0 No alias Putative uncharacterized protein... 0.12 OF
SPAC694.06c.1 No alias mediator of replication checkpoint 1... 0.06 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR018564 Repl_chkpnt_MRC1_dom 711 851
No external refs found!