Description : Protein involved in RNA polymerase II transcription; is constitutively recruited to the CYC1 promoter and is required for recruitment of chromatin remodeling factors for the expression of CYC1 gene; interacts genetically or physically with RNAP II, TBP, TFIIS, and chromatin remodelling factors; central domain highly conserved throughout eukaryotes; mutations confer an Spt- phenotype [Source:SGD;Acc:S000006337]
Gene families : OG_03_0003137 (OF) Phylogenetic Tree(s): OG0003137_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YPR133C | |
| Cluster | HCCA: Cluster_5 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AFR93738 | No alias | transcription factor IWS1;TFIIS helical bundle-like domain | 0.04 | OF | |
| AOA70341 | No alias | Transcription factor IIS, N-terminal | 0.02 | OF | |
| CAK45462 | No alias | TFIIS helical bundle-like domain | 0.03 | OF | |
| EAA29911 | No alias | Transcription factor IIS, N-terminal | 0.03 | OF | |
| EGR49746 | No alias | Transcription factor IIS, N-terminal | 0.04 | OF | |
| KHC83423 | No alias | transcription factor IWS1;TFIIS helical bundle-like domain | 0.03 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| CC | GO:0005634 | nucleus | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR017923 | TFIIS_N | 244 | 293 |
| No external refs found! |