Description : High-affinity copper transporter of plasma membrane; mediates nearly all copper uptake under low copper conditions; transcriptionally induced at low copper levels and degraded at high copper levels; protein increases in abundance and relocalizes from nucleus to plasma membrane upon DNA replication stress; human homolog SLC31A1 can complement a yeast ctr1 ctr3 double deletion [Source:SGD;Acc:S000006328]
Gene families : OG_03_0008456 (OF) Phylogenetic Tree(s): OG0008456_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YPR124W | |
Cluster | HCCA: Cluster_10 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA69501 | No alias | Ctr copper transporter | 0.05 | OF | |
CAG82366 | No alias | Ctr copper transporter | 0.03 | OF | |
KHC73231 | No alias | hypothetical protein;Ctr copper transporter family | 0.04 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005375 | copper ion transmembrane transporter activity | IEA | Interproscan |
CC | GO:0016021 | integral component of membrane | IEA | Interproscan |
BP | GO:0035434 | copper ion transmembrane transport | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR007274 | Cop_transporter | 132 | 281 |
No external refs found! |