Description : Essential 121 kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane prior to SNARE-mediated fusion; involved in ER and Golgi inheritance in small buds; relocalizes away from bud neck upon DNA replication stress [Source:SGD;Acc:S000006259]
Gene families : OG_03_0002878 (OF) Phylogenetic Tree(s): OG0002878_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YPR055W | |
| Cluster | HCCA: Cluster_48 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AFR98944 | No alias | exocyst complex component 4;Sec8 exocyst complex... | 0.08 | OF | |
| AOA67276 | No alias | Sec8 exocyst complex component specific domain | 0.09 | OF | |
| CAG80349 | No alias | Sec8 exocyst complex component specific domain | 0.1 | OF | |
| CAK47860 | No alias | Sec8 exocyst complex component specific domain | 0.07 | OF | |
| CBF79988 | No alias | Exocyst complex component Sec8, putative | 0.1 | OF | |
| EAA31914 | No alias | Sec8 exocyst complex component specific domain | 0.03 | OF | |
| EAL91794 | No alias | Exocyst complex component Sec8, putative | 0.14 | OF | |
| EAU92716 | No alias | Sec8 exocyst complex component specific domain-containing protein | 0.07 | OF | |
| EGR49335 | No alias | Sec8 exocyst complex component specific domain | 0.02 | OF | |
| ESU13175 | No alias | Sec8 exocyst complex component specific domain | 0.1 | OF | |
| KHC73230 | No alias | exocyst complex component 4;Sec8 exocyst complex... | 0.14 | OF | |
| MGG_03985T0 | No alias | Exocyst complex component sec8... | 0.08 | OF | |
| POW04615 | No alias | Sec8 exocyst complex component specific domain | 0.03 | OF | |
| SPCC970.09.1 | No alias | exocyst complex subunit Sec8 [Source:PomBase;Acc:SPCC970.09] | 0.1 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| CC | GO:0000145 | exocyst | IEA | Interproscan |
| BP | GO:0006904 | vesicle docking involved in exocytosis | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR007191 | Sec8_exocyst | 34 | 174 |
| No external refs found! |