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  5. YCL043C

YCL043C


Description : Protein disulfide isomerase; multifunctional oxidoreductase of the ER lumen, essential for disulfide bond formation in secretory and cell-surface proteins, processing of non-native disulfide bonds; Ero1p activator; complexes with exomannosidase, Mnl1p to facilitate the recognition of misfolded glycoproteins and the trimming of glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates, thereby accelerating ERAD; PDI1 has a paralog, EUG1, that arose from the whole genome duplication [Source:SGD;Acc:S000000548]


Gene families : OG_03_0000736 (OF) Phylogenetic Tree(s): OG0000736_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YCL043C
Cluster HCCA: Cluster_39

Target Alias Description ECC score Gene Family Method Actions
AFR98468 No alias protein disulfide-isomerase;Thioredoxin;Thioredoxin-like domain 0.05 OF
AOA70013 No alias Thioredoxin-like domain 0.07 OF
CAG79060 No alias Thioredoxin domain 0.03 OF
CAK48909 No alias protein disulfide isomerase A pdiA-Aspergillus niger 0.06 OF
CBF79378 No alias protein disulfide isomerase A 0.04 OF
EAA29931 No alias Thioredoxin domain 0.04 OF
EAU84825 No alias disulfide isomerase 0.02 OF
EDO00107 No alias Thioredoxin domain 0.04 OF
EGR47782 No alias Thioredoxin domain 0.03 OF
EJF61232 No alias Thioredoxin 0.03 OF
ESU06537 No alias disulfide-isomerase 0.04 OF
KHC71996 No alias protein disulfide isomerase;Thioredoxin-like domain 0.1 OF
MGG_05753T0 No alias Protein disulfide-isomerase [Source:UniProtKB/TrEMBL;Acc:G4MPX2] 0.02 OF
POW04396 No alias Thioredoxin domain;Thioredoxin domain;Thioredoxin-like domain 0.04 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR013766 Thioredoxin_domain 378 482
IPR013766 Thioredoxin_domain 34 136
No external refs found!