YPL249C


Description : GTPase-activating protein (GAP) for yeast Rab family members; involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; GYP5 has a paralog, GYL1, that arose from the whole genome duplication [Source:SGD;Acc:S000006170]


Gene families : OG_03_0000613 (OF) Phylogenetic Tree(s): OG0000613_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YPL249C
Cluster HCCA: Cluster_23

Target Alias Description ECC score Gene Family Method Actions
AOA65378 No alias Rab-GTPase-TBC domain 0.05 OF
CAG78372 No alias Rab-GTPase-TBC domain 0.07 OF
CAK38869 No alias Rab-GTPase-TBC domain 0.02 OF
CBF85940 No alias GTPase activating protein 0.05 OF
EAA33160 No alias Rab-GTPase-TBC domain 0.02 OF
EAA34192 No alias Rab-GTPase-TBC domain 0.02 OF
EAL89728 No alias GTPase activating protein (Gyp5), putative 0.03 OF
EGR50929 No alias Rab-GTPase-TBC domain 0.03 OF
ESU05838 No alias Rab-GTPase-TBC domain 0.03 OF
MGG_03253T0 No alias GTPase-activating protein GYP5... 0.02 OF
SPAC26F1.09.1 No alias GTPase activating protein Gyp51 (predicted)... 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR000195 Rab-GTPase-TBC_dom 455 648
No external refs found!