Description : RNA 5'-triphosphatase involved in mRNA 5' capping; subunit of mRNA capping enzyme, which is a heterotetramer composed of a Cet1p homodimer and two molecules of guanylyltransferase Ceg1p; Cet1p also has a role in regulation of RNAPII pausing at promoter-proximal sites; interaction between Cet1p and Ceg1p is required for Ceg1p nuclear import; mammalian enzyme is single bifunctional polypeptide; human homolog RNGTT can complement yeast cet1 null mutant [Source:SGD;Acc:S000006149]
Gene families : OG_03_0001274 (OF) Phylogenetic Tree(s): OG0001274_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YPL228W | |
| Cluster | HCCA: Cluster_32 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AFR95834 | No alias | mRNA-capping enzyme subunit beta;mRNA capping enzyme, beta chain | 0.03 | OF | |
| AOA69271 | No alias | mRNA triphosphatase Cet1-like | 0.06 | OF | |
| CAG77945 | No alias | mRNA triphosphatase Cet1-like | 0.05 | OF | |
| CAK38597 | No alias | mRNA capping enzyme, beta chain | 0.01 | OF | |
| EAA28799 | No alias | mRNA triphosphatase Cet1-like | 0.08 | OF | |
| EGR48458 | No alias | mRNA triphosphatase Cet1-like | 0.03 | OF | |
| EJF56647 | No alias | mRNA capping enzyme, beta chain | 0.02 | OF | |
| ESU13767 | No alias | mRNA triphosphatase Cet1-like | 0.03 | OF | |
| KHC71171 | No alias | mRNA-capping enzyme subunit beta;"mRNA capping enzyme,... | 0.03 | OF | |
| MGG_05990T0 | No alias | Putative uncharacterized protein... | 0.04 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0004651 | polynucleotide 5'-phosphatase activity | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR004206 | mRNA_triPase_Cet1 | 279 | 497 |
| No external refs found! |