Description : ATPase component of heat shock protein Hsp90 chaperone complex; serves as nucleotide exchange factor to load ATP onto the SSA class of cytosolic Hsp70s; plays a role in prion propagation and determining prion variants; binds unfolded proteins; member of Hsp110 subclass of HSP70 proteins; deletion results in spindle elongation in S phase; SSE1 has a paralog, SSE2, that arose from the whole genome duplication [Source:SGD;Acc:S000006027]
Gene families : OG_03_0001318 (OF) Phylogenetic Tree(s): OG0001318_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YPL106C | |
| Cluster | HCCA: Cluster_30 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AFR98435 | No alias | heat shock 70kDa protein 4;Hsp70 protein | 0.15 | OF | |
| AOA65955 | No alias | Heat shock protein 70 family | 0.15 | OF | |
| CAG79487 | No alias | Heat shock protein 70 family | 0.17 | OF | |
| CAK45502 | No alias | Hsp70 protein | 0.13 | OF | |
| CBF88261 | No alias | heat shock protein | 0.14 | OF | |
| EAL90593 | No alias | Hsp70 chaperone Hsp88 | 0.07 | OF | |
| EAU90789 | No alias | heat shock protein | 0.07 | OF | |
| EDN96960 | No alias | Heat shock protein 70 family | 0.06 | OF | |
| EGR44255 | No alias | Heat shock protein 70 family | 0.06 | OF | |
| EJF55487 | No alias | Hsp70 protein | 0.01 | OF | |
| ESA43073 | No alias | Heat shock protein 70 family | 0.03 | OF | |
| ESA43074 | No alias | Heat shock protein 70 family | 0.03 | OF | |
| ESU07320 | No alias | heat shock protein Hsp88 | 0.11 | OF | |
| KHC83378 | No alias | heat shock protein 110kDa;Hsp70 protein | 0.22 | OF | |
| POV94575 | No alias | Heat shock protein 70 family | 0.29 | OF | |
| POW11773 | No alias | Heat shock protein 70 family | 0.33 | OF | |
| SPAC110.04c.1 | No alias | heat shock protein Pss1 [Source:PomBase;Acc:SPAC110.04c] | 0.16 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No GO annotation available for this sequence |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR013126 | Hsp_70_fam | 5 | 642 |
| No external refs found! |