Description : Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase); cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis; human ACAT1 functionally complements the growth defect caused by repression of ERG10 expression [Source:SGD;Acc:S000005949]
Gene families : OG_03_0000612 (OF) Phylogenetic Tree(s): OG0000612_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YPL028W | |
Cluster | HCCA: Cluster_17 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR93774 | No alias | acetyl-CoA C-acetyltransferase;Thiolase, C-terminal... | 0.15 | OF | |
AOA65408 | No alias | Thiolase, N-terminal | 0.05 | OF | |
CAG82888 | No alias | Thiolase, C-terminal | 0.03 | OF | |
CAK47115 | No alias | Thiolase, C-terminal domain | 0.02 | OF | |
CBF84799 | No alias | acetyl-CoA acetyltransferase, putative | 0.07 | OF | |
EAA36466 | No alias | Thiolase, N-terminal | 0.04 | OF | |
EDN95946 | No alias | Thiolase, C-terminal | 0.04 | OF | |
EGR47147 | No alias | Thiolase, N-terminal | 0.06 | OF | |
ESU15881 | No alias | acetyl-CoA acetyltransferase IB | 0.19 | OF | |
KHC81483 | No alias | acetyl-CoA acetyltransferase IB;"Thiolase, N-terminal... | 0.23 | OF | |
MGG_13499T0 | No alias | Acetyl-CoA acetyltransferase [Source:UniProtKB/TrEMBL;Acc:G4N745] | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0016747 | transferase activity, transferring acyl groups other than amino-acyl groups | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |