Description : Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase); cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis; human ACAT1 functionally complements the growth defect caused by repression of ERG10 expression [Source:SGD;Acc:S000005949]

Gene families : OG_03_0000612 (OF) Phylogenetic Tree(s): OG0000612_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YPL028W
Cluster HCCA: Cluster_17

Target Alias Description ECC score Gene Family Method Actions
AFR93774 No alias acetyl-CoA C-acetyltransferase;Thiolase, C-terminal... 0.15 OF
AOA65408 No alias Thiolase, N-terminal 0.05 OF
CAG82888 No alias Thiolase, C-terminal 0.03 OF
CAK47115 No alias Thiolase, C-terminal domain 0.02 OF
CBF84799 No alias acetyl-CoA acetyltransferase, putative 0.07 OF
EAA36466 No alias Thiolase, N-terminal 0.04 OF
EDN95946 No alias Thiolase, C-terminal 0.04 OF
EGR47147 No alias Thiolase, N-terminal 0.06 OF
ESU15881 No alias acetyl-CoA acetyltransferase IB 0.19 OF
KHC81483 No alias acetyl-CoA acetyltransferase IB;"Thiolase, N-terminal... 0.23 OF
MGG_13499T0 No alias Acetyl-CoA acetyltransferase [Source:UniProtKB/TrEMBL;Acc:G4N745] 0.02 OF

Type GO Term Name Evidence Source
MF GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR020617 Thiolase_C 274 397
IPR020616 Thiolase_N 5 266
No external refs found!