Description : Essential protein that binds ribosomal protein L11; required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis; localizes to the nucleolus and in foci along nuclear periphery; cooperates with Ebp2p and Mps3p to mediate telomere clustering by binding Sir4p, but is not involved in telomere tethering; mouse homolog shows altered expression in Huntington's disease model mice [Source:SGD;Acc:S000005820]
Gene families : OG_03_0003282 (OF) Phylogenetic Tree(s): OG0003282_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YOR294W | |
Cluster | HCCA: Cluster_16 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR98507 | No alias | hypothetical protein;Ribosome biogenesis regulatory... | 0.04 | OF | |
AOA66596 | No alias | Ribosomal biogenesis regulatory protein | 0.15 | OF | |
CAG83930 | No alias | Ribosomal biogenesis regulatory protein | 0.09 | OF | |
CAK41501 | No alias | Ribosome biogenesis regulatory protein (RRS1) | 0.15 | OF | |
CBF75484 | No alias | ribosome biogenesis protein | 0.19 | OF | |
EAA34644 | No alias | Ribosomal biogenesis regulatory protein | 0.03 | OF | |
EAL87028 | No alias | ribosome biogenesis protein (Rrs1), putative | 0.21 | OF | |
EAU84446 | No alias | Ribosomal biogenesis regulatory protein | 0.08 | OF | |
EED78367 | No alias | Ribosomal biogenesis regulatory protein | 0.04 | OF | |
EGR50481 | No alias | Ribosomal biogenesis regulatory protein | 0.03 | OF | |
ESU13302 | No alias | regulator of ribosome biosynthesis | 0.17 | OF | |
KHC82880 | No alias | hypothetical protein;Ribosome biogenesis regulatory... | 0.09 | OF | |
MGG_09302T0 | No alias | Ribosome biogenesis protein [Source:UniProtKB/TrEMBL;Acc:G4MQQ2] | 0.05 | OF | |
POW16859 | No alias | Ribosomal biogenesis regulatory protein | 0.02 | OF | |
SPBC29A3.16.1 | No alias | ribosome biogenesis protein Rrs1 [Source:PomBase;Acc:SPBC29A3.16] | 0.05 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0005634 | nucleus | IEA | Interproscan |
BP | GO:0042254 | ribosome biogenesis | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR007023 | Ribosom_reg | 18 | 199 |
No external refs found! |