YOR259C

Description : ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in degradation of ubiquitinated substrates; contributes preferentially to ERAD; required for spindle pole body duplication; mainly nuclear localization [Source:SGD;Acc:S000005785]

Gene families : OG_03_0001986 (OF) Phylogenetic Tree(s): OG0001986_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YOR259C
Cluster	HCCA: Cluster_33

Target	Alias	Description	ECC score	Gene Family Method
AFR97308	No alias	26S protease regulatory subunit 10B;AAA+ lid...	0.23	OF
AOA69440	No alias	Proteasomal ATPase OB C-terminal domain	0.16	OF
CAG79841	No alias	ATPase, AAA-type, core	0.25	OF
CAK43348	No alias	AAA+ lid domain	0.26	OF
CBF81287	No alias	hypothetical protein similar to PSMC6 subunit	0.13	OF
EAA29624	No alias	ATPase, AAA-type, core	0.33	OF
EAL88533	No alias	proteasome regulatory particle subunit Rpt4, putative	0.2	OF
EAU90333	No alias	ATPase	0.17	OF
EDO01596	No alias	AAA ATPase, AAA+ lid domain	0.12	OF
EGR47620	No alias	AAA ATPase, AAA+ lid domain	0.33	OF
EJF59072	No alias	AAA+ lid domain	0.05	OF
ESU06486	No alias	ATPase, AAA-type, core	0.25	OF
KHC71346	No alias	26S protease subunit RPT4;Proteasomal ATPase OB...	0.21	OF
MGG_00330T0	No alias	26S protease subunit rpt4 [Source:UniProtKB/TrEMBL;Acc:G4NCY2]	0.03	OF
POW07133	No alias	Proteasomal ATPase OB C-terminal domain;AAA ATPase, AAA+...	0.04	OF
SPCC1682.16.1	No alias	19S proteasome regulatory subunit Rpt4 (predicted)...	0.09	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
MF	GO:0008144	drug binding	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR032501	Prot_ATP_ID_OB	105	160
IPR041569	AAA_lid_3	374	416
IPR003959	ATPase_AAA_core	218	351

External Links

No external refs found!

YOR259C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation