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  5. YOR232W

YOR232W


Description : Mitochondrial matrix cochaperone; nucleotide release factor for Ssc1p in protein translocation and folding; also acts as cochaperone for Ssq1p in folding of Fe-S cluster proteins; acts as oxidative sensor to regulate mitochondrial Ssc1p; in presence of oxidative stress, dimeric Mge1p becomes a monomer and unable to regulate Ssc1p function; homolog of E. coli GrpE and human Mge1 (GRPEL1), which also responds to oxidative stress [Source:SGD;Acc:S000005758]


Gene families : OG_03_0003320 (OF) Phylogenetic Tree(s): OG0003320_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YOR232W
Cluster HCCA: Cluster_27

Target Alias Description ECC score Gene Family Method Actions
AFR98077 No alias molecular chaperone GrpE 0.03 OF
AOA65857 No alias GrpE nucleotide exchange factor 0.03 OF
CAK37477 No alias GrpE 0.07 OF
CBF69861 No alias mitochondrial co-chaperone GrpE, putative 0.03 OF
EAA27729 No alias GrpE nucleotide exchange factor 0.05 OF
EAL93598 No alias mitochondrial co-chaperone GrpE, putative 0.06 OF
EAU88536 No alias mitochondrial grpe 0.05 OF
ESU05468 No alias GrpE nucleotide exchange factor 0.04 OF
MGG_03214T0 No alias Putative uncharacterized protein... 0.04 OF

Type GO Term Name Evidence Source
MF GO:0000774 adenyl-nucleotide exchange factor activity IEA Interproscan
BP GO:0006457 protein folding IEA Interproscan
MF GO:0042803 protein homodimerization activity IEA Interproscan
MF GO:0051087 chaperone binding IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR000740 GrpE 55 224
No external refs found!