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  5. YOR181W

YOR181W


Description : Actin assembly factor; C-terminal WCA domain activates Arp2/3 complex-mediated nucleation of branched actin filaments, polyproline domain nucleates actin filaments independent of Arp2/3; mutants are defective in endocytosis, bud site selection, cytokinesis; human homolog WAS (Wiskott-Aldrich Syndrome) implicated in severe immunodeficiency; human WAS complements yeast null mutant, but only in presence of WIPF1, which mediates localization of WAS to cortical patches [Source:SGD;Acc:S000005707]


Gene families : OG_03_0001321 (OF) Phylogenetic Tree(s): OG0001321_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YOR181W
Cluster HCCA: Cluster_5

Target Alias Description ECC score Gene Family Method Actions
AOA66538 No alias WH2 domain 0.03 OF
CAG83460 No alias WH2 domain 0.04 OF
CAK41243 No alias WH1 domain 0.02 OF
EAL85786 No alias actin associated protein Wsp1, putative 0.04 OF
ESU14661 No alias WH1/EVH1 domain 0.04 OF
KHC69704 No alias hypothetical protein;WH1 domain;WH2 motif 0.03 OF
MGG_02802T0 No alias Putative uncharacterized protein... 0.02 OF
SPAC4F10.15c.1 No alias WASp homolog [Source:PomBase;Acc:SPAC4F10.15c] 0.03 OF

Type GO Term Name Evidence Source
MF GO:0003779 actin binding IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR000697 WH1/EVH1_dom 14 123
IPR003124 WH2_dom 544 571
No external refs found!