Description : Profilin; binds actin, phosphatidylinositol 4,5-bisphosphate, and polyproline regions; involved in cytoskeleton organization; required for normal timing of actin polymerization in response to thermal stress; protein abundance increases in response to DNA replication stress; highly conserved protein; human PFN1 (profilin 1) complements temperature sensitive pfy1 mutants, PFN1 mutations are a rare cause of ALS [Source:SGD;Acc:S000005648]

Gene families : OG_03_0002187 (OF) Phylogenetic Tree(s): OG0002187_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YOR122C
Cluster HCCA: Cluster_24

Target Alias Description ECC score Gene Family Method Actions
EAL84453 No alias profilin Pfy1, putative 0.02 OF
EDN98219 No alias Profilin 0.03 OF
EGR52025 No alias Profilin 0.01 OF
KHC83554 No alias profilin;Profilin 0.02 OF
POW02490 No alias Profilin 0.02 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR005455 PFN 1 126
No external refs found!