KHC79064

Description : dynein heavy chain 1, cytosolic;Microtubule-binding stalk of dynein motor;P-loop containing dynein motor region D4;Dynein heavy chain region D6 P-loop domain;Dynein heavy chain AAA lid domain;"Dynein heavy chain, N-terminal region 2";AAA+ lid domain;"Dynein heavy chain, N-terminal region 1";ATP-binding dynein motor region;Hydrolytic ATP binding site of dynein motor region

Gene families : OG_03_0001136 (OF) Phylogenetic Tree(s): OG0001136_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: KHC79064
Cluster	HCCA: Cluster_25

Target	Alias	Description	ECC score	Gene Family Method
AFR96214	No alias	dynein heavy chain 1, cytosolic;Dynein heavy chain...	0.1	OF
AOA68102	No alias	Dynein heavy chain, domain-1	0.12	OF
CAG80308	No alias	P-loop containing dynein motor region	0.06	OF
CAK48678	No alias	Dynein heavy chain AAA lid domain	0.12	OF
CBF90163	No alias	nudA description	0.11	OF
EAL91432	No alias	dynein heavy chain	0.25	OF
EAU92970	No alias	dynein	0.14	OF
EDN92623	No alias	Dynein heavy chain, hydrolytic ATP-binding dynein motor region	0.13	OF
EFI28556	No alias	cytoplasmic dynein heavy chain 1	0.02	OF
EGR51787	No alias	Dynein heavy chain region D6 P-loop domain	0.02	OF
EJF58422	No alias	Dynein heavy chain AAA lid domain	0.09	OF
EJF58846	No alias	Dynein heavy chain, N-terminal region 1	0.04	OF
ESA43035	No alias	Dynein heavy chain, coiled coil stalk	0.07	OF
ESA43036	No alias	Dynein heavy chain, coiled coil stalk	0.07	OF
ESU16215	No alias	dynein heavy chain	0.07	OF
MGG_11205T0	No alias	Dynein heavy chain [Source:UniProtKB/TrEMBL;Acc:G4MSJ0]	0.05	OF
POW15832	No alias	Dynein heavy chain, C-terminal domain;Dynein heavy...	0.02	OF
SPAC1093.06c.1	No alias	minus-end directed microtubule motor, dynein heavy chain...	0.07	OF
YKR054C	No alias	Cytoplasmic heavy chain dynein; microtubule motor...	0.33	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003774	motor activity	None	Extended
MF	GO:0003777	microtubule motor activity	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005875	microtubule associated complex	None	Extended
BP	GO:0006928	movement of cell or subcellular component	None	Extended
BP	GO:0007017	microtubule-based process	None	Extended
BP	GO:0007018	microtubule-based movement	IEA	Interproscan
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
CC	GO:0030286	dynein complex	IEA	Interproscan
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
CC	GO:1902494	catalytic complex	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR024743	Dynein_HC_stalk	3066	3398
IPR024317	Dynein_heavy_chain_D4_dom	2780	3050
IPR004273	Dynein_heavy_D6_P-loop	3861	3966
IPR041658	AAA_lid_11	3978	4134
IPR013602	Dynein_heavy_dom-2	1253	1650
IPR041589	DNAH3_AAA_lid_1	2649	2734
IPR013594	Dynein_heavy_dom-1	202	749
IPR035706	AAA_9	3426	3639
IPR041466	Dynein_AAA5_ext	2302	2421
IPR035699	AAA_6	1786	2119

External Links

No external refs found!

KHC79064

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation