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  5. YOR048C

YOR048C


Description : Nuclear 5' to 3' single-stranded RNA exonuclease; involved in RNA metabolism, including rRNA and snoRNA processing, as well as poly (A+) dependent and independent mRNA transcription termination; required for cotranscriptional pre-rRNA cleavage; displaces Cdk1p from elongating transcripts, especially as RNAPII reaches the poly(A) site, negatively regulates phosphorylation of the CTD of RNAPII, and inhibits RNAPII transcriptional elongation [Source:SGD;Acc:S000005574]


Gene families : OG_03_0002838 (OF) Phylogenetic Tree(s): OG0002838_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YOR048C
Cluster HCCA: Cluster_63

Target Alias Description ECC score Gene Family Method Actions
AOA69009 No alias Putative 5-3 exonuclease 0.04 OF
CAG80989 No alias Putative 5-3 exonuclease 0.06 OF
CAK45649 No alias XRN 5'-3' exonuclease N-terminus 0.08 OF
CBF88946 No alias 5'-3' exoribonuclease 2 0.06 OF
EAA27029 No alias Xrn1, helical domain 0.05 OF
EAL90705 No alias 5'->3' exoribonculease Dhp1 0.13 OF
EDN98683 No alias Xrn1, helical domain 0.03 OF
ESU18075 No alias 5'-3' exoribonuclease 2 0.06 OF
KHC78056 No alias 5'-3' exoribonuclease 2;XRN 5'-3' exonuclease... 0.17 OF
MGG_11426T0 No alias 5'-3' exoribonuclease 2 [Source:UniProtKB/TrEMBL;Acc:G4NC70] 0.05 OF
SPAC26A3.12c.1 No alias 5'-3' exoribonuclease Dhp1 [Source:PomBase;Acc:SPAC26A3.12c] 0.05 OF

Type GO Term Name Evidence Source
MF GO:0003676 nucleic acid binding IEA Interproscan
MF GO:0004527 exonuclease activity IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR041412 Xrn1_helical 504 876
IPR041412 Xrn1_helical 314 480
IPR004859 Put_53exo 1 253
No external refs found!