Description : Nuclear 5' to 3' single-stranded RNA exonuclease; involved in RNA metabolism, including rRNA and snoRNA processing, as well as poly (A+) dependent and independent mRNA transcription termination; required for cotranscriptional pre-rRNA cleavage; displaces Cdk1p from elongating transcripts, especially as RNAPII reaches the poly(A) site, negatively regulates phosphorylation of the CTD of RNAPII, and inhibits RNAPII transcriptional elongation [Source:SGD;Acc:S000005574]
Gene families : OG_03_0002838 (OF) Phylogenetic Tree(s): OG0002838_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YOR048C | |
Cluster | HCCA: Cluster_63 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA69009 | No alias | Putative 5-3 exonuclease | 0.04 | OF | |
CAG80989 | No alias | Putative 5-3 exonuclease | 0.06 | OF | |
CAK45649 | No alias | XRN 5'-3' exonuclease N-terminus | 0.08 | OF | |
CBF88946 | No alias | 5'-3' exoribonuclease 2 | 0.06 | OF | |
EAA27029 | No alias | Xrn1, helical domain | 0.05 | OF | |
EAL90705 | No alias | 5'->3' exoribonculease Dhp1 | 0.13 | OF | |
EDN98683 | No alias | Xrn1, helical domain | 0.03 | OF | |
ESU18075 | No alias | 5'-3' exoribonuclease 2 | 0.06 | OF | |
KHC78056 | No alias | 5'-3' exoribonuclease 2;XRN 5'-3' exonuclease... | 0.17 | OF | |
MGG_11426T0 | No alias | 5'-3' exoribonuclease 2 [Source:UniProtKB/TrEMBL;Acc:G4NC70] | 0.05 | OF | |
SPAC26A3.12c.1 | No alias | 5'-3' exoribonuclease Dhp1 [Source:PomBase;Acc:SPAC26A3.12c] | 0.05 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003676 | nucleic acid binding | IEA | Interproscan |
MF | GO:0004527 | exonuclease activity | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |