Description : Hsp90 cochaperone; regulates spatial organization of amyloid-like proteins in the cytosol, thereby buffering the proteotoxicity caused by amyloid-like proteins; interacts with the Ssa group of the cytosolic Hsp70 chaperones and activates Ssa1p ATPase activity; interacts with Hsp90 chaperones and inhibits their ATPase activity; homolog of mammalian Hop [Source:SGD;Acc:S000005553]

Gene families : OG_03_0003654 (OF) Phylogenetic Tree(s): OG0003654_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YOR027W
Cluster HCCA: Cluster_30

Target Alias Description ECC score Gene Family Method Actions
AFR92237 No alias stress-induced-phosphoprotein 1;STI1... 0.12 OF
AOA67224 No alias STI1 domain 0.22 OF
CAG81927 No alias STI1 domain 0.21 OF
CAK41009 No alias STI1 domain 0.11 OF
CBF82501 No alias heat shock protein 0.12 OF
EAA35312 No alias Tetratricopeptide repeat 0.08 OF
EAL84708 No alias heat shock protein (Sti1), putative 0.14 OF
EDO03532 No alias Tetratricopeptide repeat 0.07 OF
ESU05992 No alias Tetratricopeptide repeat 0.11 OF
KHC75085 No alias stress-induced-phosphoprotein 1;Tetratricopeptide... 0.2 OF
MGG_08980T0 No alias Stress-induced-phosphoprotein 1... 0.03 OF
POV98943 No alias Tetratricopeptide repeat;Tetratricopeptide repeat;TPR... 0.19 OF
SPCC645.14c.1 No alias chaperone activator Sti1 (predicted)... 0.29 OF

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR019734 TPR_repeat 11 36
IPR019734 TPR_repeat 337 363
IPR001440 TPR_1 430 463
IPR001440 TPR_1 75 106
IPR041243 STI1 528 580
IPR041243 STI1 138 193
No external refs found!