YOR022C

Description : DDHD domain-containing phospholipase A1; mitochondrial matrix enzyme with sn-1-specific activity, hydrolyzing cardiolipin, PE, PC, PG and PA; implicated in remodeling of mitochondrial phospholipids; antagonistically regulated by Aft1p and Aft2p; in humans, mutations in DDHD1 and DDHD2 genes cause specific types of hereditary spastic paraplegia, while DDL1-defective yeast share similar phenotypes such as mitochondrial dysfunction and defects in lipid metabolism [Source:SGD;Acc:S000005548]

Gene families : OG_03_0005120 (OF) Phylogenetic Tree(s): OG0005120_tree

Sequence : coding (download), protein (download)

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Type	Description	Actions
Neighborhood	HRR: YOR022C
Cluster	HCCA: Cluster_48

Target	Alias	Description	ECC score	Gene Family Method	Actions
CBF70815	No alias	DDHD domain protein	0.02	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
MF	GO:0046872	metal ion binding	IEA	Interproscan

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR004177	DDHD_dom	519	699

External Links

No external refs found!

YOR022C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation