Description : Plasma membrane sterol transporter of the ATP-binding cassette family; required, along with Pdr11p, for uptake of exogenous sterols and their incorporation into the plasma membrane; activity is stimulated by phosphatidylserine; sterol uptake is required for anaerobic growth because sterol biosynthesis requires oxygen; AUS1 has a paralog, PDR11, that arose from the whole genome duplication [Source:SGD;Acc:S000005537]

Gene families : OG_03_0000022 (OF) Phylogenetic Tree(s): OG0000022_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YOR011W
Cluster HCCA: Cluster_4

Target Alias Description ECC score Gene Family Method Actions
AFR95261 No alias ATP-binding cassette transporter;ABC... 0.01 OF
AFR98586 No alias ABC transporter PMR5;ABC-2 type transporter;CDR ABC transporter 0.02 OF
CBF79672 No alias ABC transporter protein 0.02 OF
EED77030 No alias ABC-2 type transporter 0.02 OF
ESU13641 No alias ABC transporter-like 0.03 OF
KHC77632 No alias opaque-specific ABC transporter CDR3;ABC-transporter... 0.02 OF
MGG_13624T0 No alias ABC transporter CDR4 [Source:UniProtKB/TrEMBL;Acc:G4N9L5] 0.02 OF

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA Interproscan
CC GO:0016020 membrane IEA Interproscan
CC GO:0016021 integral component of membrane IEA Interproscan
MF GO:0016887 ATPase activity IEA Interproscan
MF GO:0042626 ATPase-coupled transmembrane transporter activity IEA Interproscan
BP GO:0055085 transmembrane transport IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR013525 ABC_2_trans 1062 1273
IPR013525 ABC_2_trans 370 579
IPR010929 PDR_CDR_ABC 591 668
IPR003439 ABC_transporter-like 49 199
IPR003439 ABC_transporter-like 776 906
No external refs found!