Description : Glutamine-rich cytoplasmic cochaperone; serves as a scaffold bringing together Get4, Get5p, and other TRC complex members that are required to mediate posttranslational insertion of tail-anchored proteins into the ER membrane; interacts with the prion domain of Sup35p; amyloid sensor; plays a role in targeting chaperones to prion aggregates; similar to human cochaperone SGT; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000005533]

Gene families : OG_03_0000903 (OF) Phylogenetic Tree(s): OG0000903_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YOR007C
Cluster HCCA: Cluster_30

Target Alias Description ECC score Gene Family Method Actions
AFR92421 No alias cytoplasmic protein;Tetratricopeptide... 0.07 OF
AOA65391 No alias SGTA, homodimerisation domain 0.18 OF
CAG81942 No alias Tetratricopeptide repeat 0.03 OF
ESU09050 No alias SGTA, homodimerisation domain 0.04 OF
KHC81344 No alias hypothetical protein;Tetratricopeptide... 0.11 OF
MGG_05438T0 No alias Hsc70 cochaperone [Source:UniProtKB/TrEMBL;Acc:G4MLQ8] 0.04 OF

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR032374 SGTA_dimer 4 70
IPR001440 TPR_1 171 203
No external refs found!