Description : Glutamine-rich cytoplasmic cochaperone; serves as a scaffold bringing together Get4, Get5p, and other TRC complex members that are required to mediate posttranslational insertion of tail-anchored proteins into the ER membrane; interacts with the prion domain of Sup35p; amyloid sensor; plays a role in targeting chaperones to prion aggregates; similar to human cochaperone SGT; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000005533]
Gene families : OG_03_0000903 (OF) Phylogenetic Tree(s): OG0000903_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YOR007C | |
Cluster | HCCA: Cluster_30 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR92421 | No alias | cytoplasmic protein;Tetratricopeptide... | 0.07 | OF | |
AOA65391 | No alias | SGTA, homodimerisation domain | 0.18 | OF | |
CAG81942 | No alias | Tetratricopeptide repeat | 0.03 | OF | |
ESU09050 | No alias | SGTA, homodimerisation domain | 0.04 | OF | |
KHC81344 | No alias | hypothetical protein;Tetratricopeptide... | 0.11 | OF | |
MGG_05438T0 | No alias | Hsc70 cochaperone [Source:UniProtKB/TrEMBL;Acc:G4MLQ8] | 0.04 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |