Description : Trans-golgi network aminophospholipid translocase (flippase); maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation, endocytosis, protein trafficking between the Golgi and endosomal system and the cellular response to mating pheromone; autoinhibited by its C-terminal tail; localizes to the trans-Golgi network; mutations in human homolog ATP8B1 result in liver disease [Source:SGD;Acc:S000000024]
Gene families : OG_03_0000096 (OF) Phylogenetic Tree(s): OG0000096_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YAL026C | |
| Cluster | HCCA: Cluster_8 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AFR92516 | No alias | phospholipid-transporting ATPase;E1-E2 ATPase;Cation... | 0.02 | OF | |
| AFR98706 | No alias | phospholipid-translocating... | 0.02 | OF | |
| AOA67785 | No alias | P-type ATPase, N-terminal | 0.06 | OF | |
| AOA69533 | No alias | P-type ATPase, N-terminal | 0.04 | OF | |
| CAG79643 | No alias | Cation transport ATPase (P-type) | 0.03 | OF | |
| CAK97140 | No alias | Phospholipid-translocating P-type ATPase C-terminal | 0.02 | OF | |
| EAL89767 | No alias | phospholipid-transporting ATPase (DRS2), putative | 0.03 | OF | |
| EAU88889 | No alias | phospholipid-translocating ATPase | 0.02 | OF | |
| EAU91520 | No alias | calcium transporting ATPase | 0.02 | OF | |
| EGR52241 | No alias | Cation transport ATPase (P-type) | 0.02 | OF | |
| EJF55732 | No alias | Phospholipid-translocating P-type ATPase C-terminal | 0.03 | OF | |
| EJF61625 | No alias | Phospholipid-translocating ATPase N-terminal | 0.03 | OF | |
| ESU12881 | No alias | Interpro Signature:E1-E2 ATPase | 0.03 | OF | |
| KHC74971 | No alias | phospholipid-translocating P-type ATPase,... | 0.03 | OF | |
| KHC79260 | No alias | phospholipid-translocating P-type ATPase,... | 0.08 | OF | |
| MGG_00111T0 | No alias | Phospholipid-transporting ATPase 1... | 0.02 | OF | |
| MGG_02767T0 | No alias | Phospholipid-transporting ATPase 1... | 0.02 | OF | |
| SPBC887.12.1 | No alias | P-type ATPase (predicted) [Source:PomBase;Acc:SPBC887.12] | 0.03 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No GO annotation available for this sequence |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| No external refs found! |