Description : tRNA methyltransferase; methylates the N-1 position of guanine at position 9 in tRNAs; protein abundance increases in response to DNA replication stress; member of the SPOUT (SpoU-TrmD) methyltransferase family; human ortholog TRMT10A plays a role in the pathogenesis of microcephaly and early onset diabetes; an 18-mer originates from the TRM10 locus; genetic analysis shows the 18-mer is the translation regulator [Source:SGD;Acc:S000005453]

Gene families : OG_03_0003775 (OF) Phylogenetic Tree(s): OG0003775_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YOL093W
Cluster HCCA: Cluster_43

Target Alias Description ECC score Gene Family Method Actions
AFR93784 No alias tRNA (guanine-N(1)-)-methyltransferase;tRNA... 0.02 OF
CBF83571 No alias tRNA 0.03 OF
KHC81685 No alias tRNA (guanine-N(1)-)-methyltransferase;tRNA... 0.03 OF
MGG_00880T0 No alias tRNA (Guanine-N(1)-)-methyltransferase... 0.04 OF
SPAC6B12.09.1 No alias tRNA m(1)G methyltransferase Trm10... 0.06 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR016009 tRNA_MeTrfase_TRMD/TRM10 105 276
No external refs found!