Description : tRNA methyltransferase; methylates the N-1 position of guanine at position 9 in tRNAs; protein abundance increases in response to DNA replication stress; member of the SPOUT (SpoU-TrmD) methyltransferase family; human ortholog TRMT10A plays a role in the pathogenesis of microcephaly and early onset diabetes; an 18-mer originates from the TRM10 locus; genetic analysis shows the 18-mer is the translation regulator [Source:SGD;Acc:S000005453]
Gene families : OG_03_0003775 (OF) Phylogenetic Tree(s): OG0003775_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YOL093W | |
Cluster | HCCA: Cluster_43 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR93784 | No alias | tRNA (guanine-N(1)-)-methyltransferase;tRNA... | 0.02 | OF | |
CBF83571 | No alias | tRNA | 0.03 | OF | |
KHC81685 | No alias | tRNA (guanine-N(1)-)-methyltransferase;tRNA... | 0.03 | OF | |
MGG_00880T0 | No alias | tRNA (Guanine-N(1)-)-methyltransferase... | 0.04 | OF | |
SPAC6B12.09.1 | No alias | tRNA m(1)G methyltransferase Trm10... | 0.06 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR016009 | tRNA_MeTrfase_TRMD/TRM10 | 105 | 276 |
No external refs found! |