Description : GTPase-activating protein; negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions; IRA2 has a paralog, IRA1, that arose from the whole genome duplication; defects in human homolog NF1 are associated with neurofibromatosis [Source:SGD;Acc:S000005441]

Gene families : OG_03_0004712 (OF) Phylogenetic Tree(s): OG0004712_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YOL081W
Cluster HCCA: Cluster_19

Target Alias Description ECC score Gene Family Method Actions
EGR44283 No alias Ras GTPase-activating domain 0.04 OF
KHC83982 No alias hypothetical protein;GTPase-activator protein for Ras-like GTPase 0.03 OF

Type GO Term Name Evidence Source
BP GO:0043087 regulation of GTPase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001936 RasGAP_dom 1785 1890
No external refs found!