YOL081W

Description : GTPase-activating protein; negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions; IRA2 has a paralog, IRA1, that arose from the whole genome duplication; defects in human homolog NF1 are associated with neurofibromatosis [Source:SGD;Acc:S000005441]

Gene families : OG_03_0004712 (OF) Phylogenetic Tree(s): OG0004712_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YOL081W
Cluster	HCCA: Cluster_19

Target	Alias	Description	ECC score	Gene Family Method	Actions
EGR44283	No alias	Ras GTPase-activating domain	0.04	OF
KHC83982	No alias	hypothetical protein;GTPase-activator protein for Ras-like GTPase	0.03	OF

Type	GO Term	Name	Evidence	Source
BP	GO:0008150	biological_process	None	Extended
BP	GO:0043087	regulation of GTPase activity	IEA	Interproscan
BP	GO:0050790	regulation of catalytic activity	None	Extended
BP	GO:0051336	regulation of hydrolase activity	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065009	regulation of molecular function	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR001936	RasGAP_dom	1785	1890

External Links

No external refs found!

YOL081W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation