Description : Protein required for flavinylation of Sdh1p; binds to Sdh1p and promotes FAD cofactor attachment, which is necessary for succinate dehydrogenase (SDH) complex assembly and activity; mutations in human ortholog PGL2 are associated with neuroendocrine tumors (paraganglioma) [Source:SGD;Acc:S000005432]
Gene families : OG_03_0001489 (OF) Phylogenetic Tree(s): OG0001489_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YOL071W | |
Cluster | HCCA: Cluster_60 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CBF74574 | No alias | TPR repeat protein | 0.02 | OF | |
EAL89475 | No alias | TPR repeat protein | 0.02 | OF | |
EDN94271 | No alias | Flavinator of succinate dehydrogenase | 0.03 | OF | |
EFI27349 | No alias | mitochondrial protein | 0.07 | OF | |
EGR52614 | No alias | Flavinator of succinate dehydrogenase | 0.03 | OF | |
KHC83618 | No alias | succinate dehydrogenase assembly factor 2,... | 0.04 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR005631 | SDH | 66 | 141 |
No external refs found! |