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YOL013C


Description : Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) of misfolded proteins; upon autoubiquitination triggers retrotranslocation of misfolded proteins to cytosol for degradation; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger; likely plays a general role in targeting proteins that persistently associate with and potentially obstruct the ER-localized translocon [Source:SGD;Acc:S000005373]


Gene families : OG_03_0000922 (OF) Phylogenetic Tree(s): OG0000922_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YOL013C
Cluster HCCA: Cluster_34

Target Alias Description ECC score Gene Family Method Actions
AFR98899 No alias E3 ubiquitin-protein ligase synoviolin;RING-H2 zinc finger domain 0.04 OF
AOA69805 No alias Zinc finger, RING-type 0.02 OF
AOA70109 No alias Zinc finger, RING-type 0.04 OF
CAG77733 No alias Zinc finger, RING-type 0.03 OF
EAA29940 No alias Zinc finger, RING-type 0.03 OF
EAU91350 No alias synoviolin 1 isoform b 0.02 OF
EGR46363 No alias Zinc finger, RING-H2-type 0.02 OF
ESU07245 No alias Zinc finger, RING-H2-type 0.02 OF
SPBC17D11.02c.1 No alias synviolin family ubiquitin-protein ligase E3, Hrd1... 0.04 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR001841 Znf_RING 348 400
No external refs found!