Description : Core component of transport protein particle (TRAPP) complexes I-III; TRAPPs are multimeric guanine nucleotide-exchange factors for GTPase Ypt1p, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII); mutation leads to defects in endocytic recycling, block in sporulation/meiosis; mutations in human homolog TRAPPC2 cause spondyloepiphyseal dysplasia tarda, TRAPPC2 can complement yeast null mutant [Source:SGD;Acc:S000000458]
Gene families : OG_03_0003600 (OF) Phylogenetic Tree(s): OG0003600_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YBR254C | |
Cluster | HCCA: Cluster_57 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CAG79081 | No alias | Trafficking protein particle complex subunit 2 | 0.06 | OF | |
ESU11459 | No alias | Trafficking protein particle complex subunit 2 | 0.02 | OF | |
KHC82913 | No alias | hypothetical protein;"Sedlin, N-terminal conserved region" | 0.03 | OF | |
SPBC11G11.04.1 | No alias | TRAPP complex subunit Trs20 (predicted)... | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR006722 | Sedlin | 7 | 171 |
No external refs found! |