YNR070W

Description : Putative transporter of the ATP-binding cassette (ABC) family; role in plasma membrane sterol incorporation; implicated in pleiotropic drug resistance; provides resistance to ethanol stress and contributes to a decreased intracellular accumulation of ethanol; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [Source:SGD;Acc:S000005353]

Gene families : OG_03_0000022 (OF) Phylogenetic Tree(s): OG0000022_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YNR070W

Target	Alias	Description	ECC score	Gene Family Method
AFR92860	No alias	ATP-binding cassette transporter;ABC-2 type...	0.03	OF
CAG83074	No alias	ABC-2 type transporter	0.01	OF
CAK37117	No alias	ABC-2 type transporter	0.02	OF
CAK41702	No alias	ABC transporter	0.03	OF
CAK96572	No alias	ABC-transporter N-terminal	0.02	OF
CBF80656	No alias	ATP-binding cassette multidrug transporter	0.03	OF
CBF83105	No alias	ABC multidrug transporter	0.01	OF
EAU92343	No alias	ABC-transporter	0.02	OF
EGR50196	No alias	ABC-2 type transporter	0.01	OF
ESU14459	No alias	ABC transporter-like	0.05	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
CC	GO:0016020	membrane	IEA	Interproscan
CC	GO:0016021	integral component of membrane	IEA	Interproscan
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	Interproscan
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042626	ATPase-coupled transmembrane transporter activity	IEA	Interproscan
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	Interproscan
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR010929	PDR_CDR_ABC	593	682
IPR003439	ABC_transporter-like	46	207
IPR003439	ABC_transporter-like	748	898
IPR013525	ABC_2_trans	373	581
IPR013525	ABC_2_trans	1045	1255

External Links

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YNR070W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation