Description : Protein involved in apoptosis; variously described as containing a BCL-2 homology (BH3) domain or as a member of the BAX inhibitor family; reported to promote apoptosis under some conditions and to inhibit it in others; localizes to ER and vacuole; may link the unfolded protein response to apoptosis via regulation of calcium-mediated signaling; translocates to mitochondria under apoptosis-inducing conditions in a process involving Mir1p and Cor1p [Source:SGD;Acc:S000005249]
Gene families : OG_03_0002933 (OF) Phylogenetic Tree(s): OG0002933_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YNL305C | |
| Cluster | HCCA: Cluster_52 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AOA69616 | No alias | Bax inhibitor 1-related | 0.03 | OF | |
| CAG82754 | No alias | Bax inhibitor 1-related | 0.04 | OF | |
| EAA35821 | No alias | Bax inhibitor 1-related | 0.02 | OF | |
| EAU91095 | No alias | glutamate binding protein | 0.01 | OF | |
| EGR46803 | No alias | Bax inhibitor 1-related | 0.02 | OF | |
| ESU15998 | No alias | Bax inhibitor 1-related | 0.02 | OF | |
| POW00745 | No alias | Bax inhibitor 1-related | 0.02 | OF | |
| SPCC576.04.1 | No alias | BAX inhibitor family protein Bxi1 [Source:PomBase;Acc:SPCC576.04] | 0.03 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No GO annotation available for this sequence |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR006214 | Bax_inhibitor_1-related | 48 | 290 |
| No external refs found! |