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YNL138W


Description : CAP (cyclase-associated protein); N-terminus binds adenylate cyclase and facilitates activation by RAS; N-terminus forms novel hexameric star-shaped shuriken structures that directly catalyze cofilin-mediated severing of actin filaments; C-terminus binds and recycles cofilin bound, ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis; N- and C-termini can function as physically separate proteins; mCAP1 is the mouse homolog [Source:SGD;Acc:S000005082]


Gene families : OG_03_0002848 (OF) Phylogenetic Tree(s): OG0002848_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YNL138W
Cluster HCCA: Cluster_34

Target Alias Description ECC score Gene Family Method Actions
AFR94473 No alias adenylyl cyclase-associated protein;Adenylate cyclase... 0.04 OF
AOA66988 No alias Adenylate cyclase-associated CAP, C-terminal 0.05 OF
CAG82969 No alias Adenylate cyclase-associated CAP, C-terminal 0.04 OF
CBF88364 No alias adenylyl cyclase-associated protein 0.02 OF
EAA33442 No alias Adenylate cyclase-associated CAP, C-terminal 0.02 OF
EAL90608 No alias adenylyl cyclase-associated protein (cap) 0.06 OF
EGR44260 No alias Adenylate cyclase-associated CAP, C-terminal 0.03 OF
KHC71365 No alias hypothetical protein;Adenylate cyclase associated (CAP)... 0.06 OF
MGG_01722T0 No alias Adenylyl cyclase-associated protein... 0.03 OF
SPCC306.09c.1 No alias adenylyl cyclase-associated protein Cap1... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0003779 actin binding IEA Interproscan
BP GO:0007010 cytoskeleton organization IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR013992 Adenylate_cyclase-assoc_CAP_N 15 347
IPR013912 Adenylate_cyclase-assoc_CAP_C 369 524
No external refs found!