Description : Protein involved in cytochrome c oxidase (Complex IV) assembly; involved in delivery of copper to Complex IV; also required for efficient formation of respiratory supercomplexes comprised of Complexes III and IV; localizes to the mitochondrial intermembrane space; ortholog implicated in cardiac defects in zebrafish and human; transcription is induced in response to the DNA-damaging agent MMS; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004857]
Gene families : OG_03_0002052 (OF) Phylogenetic Tree(s): OG0002052_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YMR244C-A | |
Cluster | HCCA: Cluster_35 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CBF76289 | No alias | conserved hypothetical protein | 0.07 | OF | |
EAA30701 | No alias | Cytochrome c oxidase, subunit VIb | 0.03 | OF | |
EAL92603 | No alias | conserved hypothetical protein | 0.05 | OF | |
EDN99771 | No alias | Cytochrome c oxidase, subunit VIb | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0005739 | mitochondrion | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR003213 | Cyt_c_oxidase_su6B | 16 | 91 |
No external refs found! |