Description : Vacuolar membrane zinc transporter; transports zinc from cytosol to vacuole for storage; also has role in resistance to zinc shock resulting from sudden influx of zinc into cytoplasm; human ortholog SLC30A10 functions as a Mn transporter and mutations in SLC30A10 cause neurotoxic accumulation of Mn in liver and brain; ZRC1 has a paralog, COT1, that arose from the whole genome duplication [Source:SGD;Acc:S000004856]
Gene families : OG_03_0000534 (OF) Phylogenetic Tree(s): OG0000534_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YMR243C | |
| Cluster | HCCA: Cluster_13 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| EDO03817 | No alias | Cation efflux protein | 0.01 | OF | |
| MGG_03634T0 | No alias | Putative uncharacterized protein... | 0.02 | OF | |
| SPAC23C11.14.1 | No alias | zinc ion transmembrane transporter Zhf1... | 0.03 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| BP | GO:0006812 | cation transport | IEA | Interproscan |
| MF | GO:0008324 | cation transmembrane transporter activity | IEA | Interproscan |
| CC | GO:0016021 | integral component of membrane | IEA | Interproscan |
| BP | GO:0055085 | transmembrane transport | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR002524 | Cation_efflux | 13 | 295 |
| No external refs found! |