YMR186W


Description : Cytoplasmic chaperone of the Hsp90 family; plays a role in determining prion variants; redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels than HSP82 and induced 2-3 fold by heat shock; contains two acid-rich unstructured regions that promote the solubility of chaperone-substrate complexes; HSC82 has a paralog, HSP82, that arose from the whole genome duplication [Source:SGD;Acc:S000004798]


Gene families : OG_03_0001080 (OF) Phylogenetic Tree(s): OG0001080_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YMR186W
Cluster HCCA: Cluster_30

Target Alias Description ECC score Gene Family Method Actions
AFR95394 No alias cation-transporting ATPase;Histidine kinase-, DNA gyrase... 0.11 OF
AFR98377 No alias hsp90-like protein;Hsp90 protein;Histidine kinase-, DNA... 0.15 OF
AOA66179 No alias Heat shock protein Hsp90 family 0.21 OF
CAG81881 No alias Histidine kinase/HSP90-like ATPase 0.16 OF
CAK40452 No alias heat shock protein sspB-Aspergillus niger 0.1 OF
CBF74248 No alias heat shock protein 90 0.16 OF
EAA32062 No alias Heat shock protein Hsp90 family 0.12 OF
EAL85888 No alias molecular chaperone and allergen Mod-E/Hsp90/Hsp1 0.09 OF
EAU88255 No alias heat shock protein 90 0.14 OF
EDO04908 No alias Heat shock protein Hsp90 family 0.06 OF
EGR46340 No alias Histidine kinase/HSP90-like ATPase 0.06 OF
EJF61122 No alias Hsp90 protein 0.02 OF
ESU07397 No alias heat shock protein 90 0.09 OF
KHC71887 No alias molecular chaperone HtpG;Hsp90 protein;"Histidine... 0.35 OF
MGG_06759T0 No alias Heat shock protein 90 [Source:UniProtKB/TrEMBL;Acc:G4MLM8] 0.08 OF
POW03394 No alias Histidine kinase-, DNA gyrase B-, and HSP90-like... 0.04 OF
POW13974 No alias Histidine kinase/HSP90-like ATPase;Heat shock protein... 0.24 OF
SPAC926.04c.1 No alias Hsp90 chaperone [Source:PomBase;Acc:SPAC926.04c] 0.28 OF

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA Interproscan
BP GO:0006457 protein folding IEA Interproscan
MF GO:0051082 unfolded protein binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR003594 HATPase_C 26 180
IPR001404 Hsp90_fam 183 691
No external refs found!