Description : Actin cortical patch component; interacts with the actin depolymerizing factor cofilin; inhibits elongation of aged ADP-actin filaments decorated with cofilin to maintain a high level of assembly-competent actin species; required to restrict cofilin localization to cortical patches; putative regulator of cytokinesis; contains WD repeats; protein increases in abundance and relocalizes from cytoplasm to plasma membrane upon DNA replication stress [Source:SGD;Acc:S000004698]
Gene families : OG_03_0002778 (OF) Phylogenetic Tree(s): OG0002778_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YMR092C | |
Cluster | HCCA: Cluster_34 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR97752 | No alias | WD-repeat protein;Anaphase-promoting complex subunit 4... | 0.1 | OF | |
CAK48891 | No alias | Anaphase-promoting complex subunit 4 WD40 domain | 0.06 | OF | |
CBF79402 | No alias | conserved hypothetical protein similar to Aip1 | 0.04 | OF | |
EAL87695 | No alias | actin cortical patch component, putative | 0.03 | OF | |
EDO02759 | No alias | WD40 repeat | 0.04 | OF | |
EGR53123 | No alias | Anaphase-promoting complex subunit 4, WD40 domain | 0.06 | OF | |
EJF56241 | No alias | WD domain, G-beta repeat | 0.03 | OF | |
KHC70738 | No alias | hypothetical protein;"WD domain, G-beta repeat" | 0.05 | OF | |
POW12322 | No alias | WD40 repeat | 0.04 | OF | |
SPAC9G1.05.1 | No alias | actin cortical patch component Aip1... | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |