Description : PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs; anchored in the ER membrane at nucleus-vacuole junctions and binds phosphatidylinositol 3-phosphate (PtdIns-3-P) in the vacuolar membrane via its Phox homology (PX) domain; expressed predominantly in late G1 to early S phase of the cell cycle; mutation affects nuclear and mitochondrial transmission to daughter buds; similar to 4 human genes, one of which (SNX14) is associated with neurological disease [Source:SGD;Acc:S000004572]

Gene families : OG_03_0003745 (OF) Phylogenetic Tree(s): OG0003745_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YML104C
Cluster HCCA: Cluster_41

Target Alias Description ECC score Gene Family Method Actions
AFR97910 No alias hypothetical protein;Regulator of G protein signaling... 0.04 OF
CAG77689 No alias Phox homologous domain 0.03 OF
EAA28340 No alias Sorting nexin, C-terminal 0.02 OF
EAU92550 No alias structural protein MDM1 0.02 OF
EDO00556 No alias Phox-associated domain 0.04 OF
POW16513 No alias Phox-associated domain;Sorting nexin, C-terminal;OTU... 0.02 OF
SPCC16A11.04.1 No alias sorting nexin Snx12 (predicted) [Source:PomBase;Acc:SPCC16A11.04] 0.05 OF

Type GO Term Name Evidence Source
MF GO:0035091 phosphatidylinositol binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR003114 Phox_assoc 86 271
IPR001683 Phox 793 899
IPR013937 Sorting_nexin_C 993 1106
No external refs found!