Description : Guanine nucleotide exchange factor (GEF) and ubiquitin receptor; involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF MUK1; required for localization of the CORVET complex to endosomes; similar to mammalian ras inhibitors; contains a Ub-interacting CUE domain [Source:SGD;Acc:S000004563]
Gene families : OG_03_0001843 (OF) Phylogenetic Tree(s): OG0001843_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
|Target||Alias||Description||ECC score||Gene Family Method||Actions|
|EJF57240||No alias||Domain of unknown function (DUF5601)||0.02||OF|
No Predicted GO terms available for this sequence
|No external refs found!|