Description : Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; affects expression of multiple genes via its role in nucleosome assembly; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; FPR3 has a paralog, FPR4, that arose from the whole genome duplication [Source:SGD;Acc:S000004539]

Gene families : OG_03_0002142 (OF) Phylogenetic Tree(s): OG0002142_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YML074C
Cluster HCCA: Cluster_5

Target Alias Description ECC score Gene Family Method Actions
AOA67928 No alias Nucleoplasmin-like domain 0.02 OF
CBF75117 No alias FK506-binding protein 4 0.02 OF
EAL88709 No alias FKBP-type peptidyl-prolyl isomerase, putative 0.02 OF
EAU91426 No alias peptidylprolyl isomerase 0.02 OF
EGR51536 No alias FKBP-type peptidyl-prolyl cis-trans isomerase domain 0.02 OF
ESU06331 No alias FK506-binding protein 0.03 OF
KHC83156 No alias FK506-binding protein 3;FKBP-type peptidyl-prolyl... 0.07 OF
SPAC27F1.06c.1 No alias FKBP-type peptidyl-prolyl cis-trans isomerase... 0.03 OF
SPBC1347.02.1 No alias FKBP-type peptidyl-prolyl cis-trans isomerase... 0.02 OF

Type GO Term Name Evidence Source
MF GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR041232 NPL 10 162
IPR001179 PPIase_FKBP_dom 319 407
No external refs found!