Description : Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; affects expression of multiple genes via its role in nucleosome assembly; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; FPR3 has a paralog, FPR4, that arose from the whole genome duplication [Source:SGD;Acc:S000004539]
Gene families : OG_03_0002142 (OF) Phylogenetic Tree(s): OG0002142_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YML074C | |
Cluster | HCCA: Cluster_5 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA67928 | No alias | Nucleoplasmin-like domain | 0.02 | OF | |
CBF75117 | No alias | FK506-binding protein 4 | 0.02 | OF | |
EAL88709 | No alias | FKBP-type peptidyl-prolyl isomerase, putative | 0.02 | OF | |
EAU91426 | No alias | peptidylprolyl isomerase | 0.02 | OF | |
EGR51536 | No alias | FKBP-type peptidyl-prolyl cis-trans isomerase domain | 0.02 | OF | |
ESU06331 | No alias | FK506-binding protein | 0.03 | OF | |
KHC83156 | No alias | FK506-binding protein 3;FKBP-type peptidyl-prolyl... | 0.07 | OF | |
SPAC27F1.06c.1 | No alias | FKBP-type peptidyl-prolyl cis-trans isomerase... | 0.03 | OF | |
SPBC1347.02.1 | No alias | FKBP-type peptidyl-prolyl cis-trans isomerase... | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |