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  5. YBR170C

YBR170C


Description : Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase; assists Cdc48p in the dislocation of misfolded, polyubiquitinated ERAD substrates that are subsequently delivered to the proteasome for degradation; also involved in the regulated destruction of resident ER membrane proteins, such as HMG-CoA reductase (Hmg1/2p) and cytoplasmic proteins (Fbp1p); role in mobilizing membrane bound transcription factors by regulated ubiquitin/proteasome-dependent processing (RUP) [Source:SGD;Acc:S000000374]


Gene families : OG_03_0001634 (OF) Phylogenetic Tree(s): OG0001634_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YBR170C
Cluster HCCA: Cluster_33

Target Alias Description ECC score Gene Family Method Actions
AFR97934 No alias nuclear protein localization protein 4;NPL4 family,... 0.04 OF
CAG79486 No alias NPL4, zinc-binding putative 0.1 OF
CBF89782 No alias Nuclear protein localization protein 4 0.02 OF
EDO01971 No alias Nuclear pore localisation protein NPL4, C-terminal 0.02 OF
EGR47631 No alias Nuclear pore localisation protein NPL4, C-terminal 0.04 OF
ESU06505 No alias Nuclear pore localisation protein NPL4, C-terminal 0.02 OF
KHC83379 No alias nuclear protein localization protein 4;"NPL4 family,... 0.05 OF
MGG_04413T1 No alias Nuclear protein localization protein 4... 0.04 OF
SPBC1711.10c.1 No alias Cdc48-Npl4-Ufd1 complex subunit Npl4 (predicted)... 0.02 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR007717 NPL4_C 259 577
IPR007716 NPL4_Zn-bd_put 113 256
No external refs found!