YLR418C


Description : Component of the Paf1p complex; binds to and modulates the activity of RNA polymerases I and II; required for expression of certain genes, modification of some histones, and telomere maintenance; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay; protein abundance increases in response to DNA replication stress; human homolog, parafibromin, is a tumour suppressor linked to breast, renal and gastric cancers [Source:SGD;Acc:S000004410]


Gene families : OG_03_0003337 (OF) Phylogenetic Tree(s): OG0003337_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YLR418C
Cluster HCCA: Cluster_46

Target Alias Description ECC score Gene Family Method Actions
AFR95537 No alias parafibromin;RNA pol II accessory factor, Cdc73 family,... 0.02 OF
AOA67696 No alias Cell division control protein 73, C-terminal 0.04 OF
CAG83675 No alias Cell division control protein 73, C-terminal 0.05 OF
EGR52656 No alias Cell division control protein 73, C-terminal 0.03 OF
ESA42870 No alias Cell division control protein 73, C-terminal 0.04 OF
ESU12296 No alias Cell division control protein 73, C-terminal 0.08 OF
KHC83073 No alias parafibromin;"RNA pol II accessory factor, Cdc73 family,... 0.03 OF
MGG_15720T0 No alias Putative uncharacterized protein... 0.02 OF
POW16255 No alias Cell division control protein 73, C-terminal 0.02 OF
SPBC17G9.02c.1 No alias RNA polymerase II accessory factor, Cdc73 family... 0.02 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR031336 CDC73_C 235 385
No external refs found!