Description : Metalloprotease; involved in N-terminal processing of pro-a-factor to mature form; expressed in both haploids and diploids; one of two yeast homologs of human insulin-degrading enzyme (hIDE); homolog Axl1p is also involved in processing of pro-a-factor [Source:SGD;Acc:S000004381]

Gene families : OG_03_0002569 (OF) Phylogenetic Tree(s): OG0002569_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YLR389C
Cluster HCCA: Cluster_34

Target Alias Description ECC score Gene Family Method Actions
AFR94313 No alias insulysin;Middle or third domain of... 0.04 OF
AOA66699 No alias Peptidase M16, C-terminal 0.06 OF
EAU88742 No alias insulin-degrading enzyme 0.02 OF
MGG_13149T0 No alias A-factor-processing enzyme [Source:UniProtKB/TrEMBL;Acc:G4MP03] 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR032632 Peptidase_M16_M 432 712
IPR007863 Peptidase_M16_C 716 898
IPR007863 Peptidase_M16_C 248 423
IPR011765 Pept_M16_N 85 221
No external refs found!