Description : TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70); stimulates ATPase activity of Ssa1p; ts mutants reduce Hsp82p function, overexpression suppresses phenotypes of HSP82 ts allele and cpr7 deletion; human homolog TTC4 complements yeast cns1 mutant [Source:SGD;Acc:S000000359]
Gene families : OG_03_0002813 (OF) Phylogenetic Tree(s): OG0002813_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YBR155W | |
| Cluster | HCCA: Cluster_13 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AFR99049 | No alias | TPR repeat-containing protein | 0.04 | OF | |
| AOA67018 | No alias | No description available | 0.1 | OF | |
| CAK96649 | No alias | No description available | 0.13 | OF | |
| CBF81909 | No alias | TPR repeat protein | 0.05 | OF | |
| EAL89198 | No alias | TPR repeat protein | 0.06 | OF | |
| EDN96998 | No alias | No description available | 0.07 | OF | |
| EED45021 | No alias | TPR repeat protein | 0.04 | OF | |
| ESU16431 | No alias | hypothetical protein | 0.06 | OF | |
| KHC82847 | No alias | hypothetical protein;"Anaphase-promoting complex,... | 0.08 | OF | |
| POW14956 | No alias | hypothetical protein | 0.05 | OF | |
| SPAC17A2.04c.1 | No alias | HSP chaperone complex subunit Cns1 (predicted)... | 0.02 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0005515 | protein binding | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR001440 | TPR_1 | 124 | 154 |
| No external refs found! |