Description : Rab family GTPase; required for endosome-to-Golgii, intra-Golgi retrograde, and retrograde Golgi-to-ER transport; temporarily at the Golgi, dissociating into the cytosol on arrival of the late Golgi GTPase Ypt32p; Golgi-localized form is GTP bound, while cytosolic form is GDP-bound; required for delivery of Atg9p to the phagophore assembly site during autophagy under heat stress, with Ypt6p for starvation induced autophagy and for the CVT pathway; homolog of mammalian Rab6 [Source:SGD;Acc:S000004252]
Gene families : OG_03_0002867 (OF) Phylogenetic Tree(s): OG0002867_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YLR262C | |
Cluster | HCCA: Cluster_51 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CBF79720 | No alias | hypothetical protein similar to small GTP-binding protein | 0.02 | OF | |
EAA32658 | No alias | Small GTPase | 0.02 | OF | |
EAL93854 | No alias | RAS small monomeric GTPase Rab6, putative | 0.04 | OF | |
EDN92527 | No alias | Small GTPase | 0.03 | OF | |
POW02720 | No alias | Small GTPase | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003924 | GTPase activity | IEA | Interproscan |
MF | GO:0005525 | GTP binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001806 | Small_GTPase | 12 | 173 |
No external refs found! |