Description : E3 ubiquitin ligase and putative helicase; involved in synthesis-dependent strand annealing-mediated homologous recombination; ensures precise end-joining along with Srs2p in the Yku70p/Yku80p/Lig4p-dependent nonhomologous end joining (NHEJ) pathway; localizes to both the mitochondrion and the nucleus; contains a Snf2/Swi2 family ATPase/helicase and a RING finger domain; interacts with Cdc48p and Smt3p; null mutant displays increased levels of spontaneous Rad52p foci [Source:SGD;Acc:S000004237]

Gene families : OG_03_0002566 (OF) Phylogenetic Tree(s): OG0002566_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YLR247C
Cluster HCCA: Cluster_48

Target Alias Description ECC score Gene Family Method Actions
AFR95130 No alias E3 ubiquitin-protein ligase SHPRH;Zinc finger, C3HC4... 0.06 OF
AOA69913 No alias Zinc finger, C3HC4 type (RING finger) 0.03 OF
CAG81848 No alias Zinc finger, RING-type 0.04 OF
EGR44978 No alias SNF2-related, N-terminal domain 0.03 OF
MGG_07487T0 No alias ATP-dependent DNA helicase [Source:UniProtKB/TrEMBL;Acc:G4N1L6] 0.02 OF
SPAC144.05.1 No alias ATP-dependent DNA helicase/ ubiquitin-protein ligase E3... 0.02 OF

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR000330 SNF2_N 294 711
No external refs found!