Description : E3 ubiquitin ligase and putative helicase; involved in synthesis-dependent strand annealing-mediated homologous recombination; ensures precise end-joining along with Srs2p in the Yku70p/Yku80p/Lig4p-dependent nonhomologous end joining (NHEJ) pathway; localizes to both the mitochondrion and the nucleus; contains a Snf2/Swi2 family ATPase/helicase and a RING finger domain; interacts with Cdc48p and Smt3p; null mutant displays increased levels of spontaneous Rad52p foci [Source:SGD;Acc:S000004237]
Gene families : OG_03_0002566 (OF) Phylogenetic Tree(s): OG0002566_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YLR247C | |
Cluster | HCCA: Cluster_48 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR95130 | No alias | E3 ubiquitin-protein ligase SHPRH;Zinc finger, C3HC4... | 0.06 | OF | |
AOA69913 | No alias | Zinc finger, C3HC4 type (RING finger) | 0.03 | OF | |
CAG81848 | No alias | Zinc finger, RING-type | 0.04 | OF | |
EGR44978 | No alias | SNF2-related, N-terminal domain | 0.03 | OF | |
MGG_07487T0 | No alias | ATP-dependent DNA helicase [Source:UniProtKB/TrEMBL;Acc:G4N1L6] | 0.02 | OF | |
SPAC144.05.1 | No alias | ATP-dependent DNA helicase/ ubiquitin-protein ligase E3... | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005524 | ATP binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000330 | SNF2_N | 294 | 711 |
No external refs found! |