Description : Plasma membrane transporter responsible for the uptake of thiamine; contributes to uptake of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (acadesine); member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia [Source:SGD;Acc:S000004227]

Gene families : OG_03_0000123 (OF) Phylogenetic Tree(s): OG0000123_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YLR237W
Cluster HCCA: Cluster_4

Target Alias Description ECC score Gene Family Method Actions
AFR97583 No alias uracil permease;Permease for cytosine/purines, uracil,... 0.03 OF
CAK38319 No alias Permease for cytosine/purines, uracil, thiamine, allantoin 0.04 OF
CBF80497 No alias conserved hypothetical protein 0.02 OF
EED78413 No alias Purine-cytosine permease 0.02 OF
EJF57376 No alias Permease for cytosine/purines, uracil, thiamine, allantoin 0.03 OF
YBL042C No alias High affinity uridine permease, localizes to the plasma... 0.03 OF

Type GO Term Name Evidence Source
CC GO:0016020 membrane IEA Interproscan
MF GO:0022857 transmembrane transporter activity IEA Interproscan
BP GO:0055085 transmembrane transport IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001248 Pur-cyt_permease 34 467
No external refs found!