Description : Plasma membrane transporter responsible for the uptake of thiamine; contributes to uptake of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (acadesine); member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia [Source:SGD;Acc:S000004227]
Gene families : OG_03_0000123 (OF) Phylogenetic Tree(s): OG0000123_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YLR237W | |
Cluster | HCCA: Cluster_4 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR97583 | No alias | uracil permease;Permease for cytosine/purines, uracil,... | 0.03 | OF | |
CAK38319 | No alias | Permease for cytosine/purines, uracil, thiamine, allantoin | 0.04 | OF | |
CBF80497 | No alias | conserved hypothetical protein | 0.02 | OF | |
EED78413 | No alias | Purine-cytosine permease | 0.02 | OF | |
EJF57376 | No alias | Permease for cytosine/purines, uracil, thiamine, allantoin | 0.03 | OF | |
YBL042C | No alias | High affinity uridine permease, localizes to the plasma... | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0016020 | membrane | IEA | Interproscan |
MF | GO:0022857 | transmembrane transporter activity | IEA | Interproscan |
BP | GO:0055085 | transmembrane transport | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001248 | Pur-cyt_permease | 34 | 467 |
No external refs found! |