YBR131W

Description : Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex, which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; involved in localizing Ypt7p to the vacuolar membrane; required for macroautophagy, the CVT pathway and mitophagy [Source:SGD;Acc:S000000335]

Gene families : OG_03_0051100 (OF) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YBR131W
Cluster	HCCA: Cluster_48

Type	GO Term	Name	Evidence	Source
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016192	vesicle-mediated transport	IEA	Interproscan
CC	GO:0032991	protein-containing complex	None	Extended
CC	GO:0035658	Mon1-Ccz1 complex	IEA	Interproscan
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR013176	Ccz1	6	702

External Links

No external refs found!

YBR131W

Expression Profile

Co-expression Networks

Functional Annotation