Description : Protein involved in SRP-independent targeting of substrates to the ER; component of an alternative ER targeting pathway that has partial functional redundancy with the GET pathway; preference for substrates with downstream transmembrane domains; interacts with Snd1p, Pho88p/Snd3p, and Sec61p-translocon subunits; can compensate for loss of SRP; role in the late endosome-vacuole interface; putative role in secretory protein quality control [Source:SGD;Acc:S000004055]
Gene families : OG_03_0004318 (OF) Phylogenetic Tree(s): OG0004318_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YLR065C | |
Cluster | HCCA: Cluster_57 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR93546 | No alias | hypothetical protein;SRP-independent targeting protein 2/TMEM208 | 0.03 | OF | |
EAA27363 | No alias | SRP-independent targeting protein 2/TMEM208 | 0.02 | OF | |
EED84695 | No alias | SRP-independent targeting protein 2/TMEM208 | 0.03 | OF | |
EGR46525 | No alias | SRP-independent targeting protein 2/TMEM208 | 0.06 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR008506 | SND2/TMEM208 | 1 | 171 |
No external refs found! |