YLR044C


Description : Major of three pyruvate decarboxylase isozymes; key enzyme in alcoholic fermentation; decarboxylates pyruvate to acetaldehyde; involved in amino acid catabolism; subject to glucose-, ethanol-, and autoregulation; activated by phosphorylation in response to glucose levels; N-terminally propionylated in vivo [Source:SGD;Acc:S000004034]


Gene families : OG_03_0000449 (OF) Phylogenetic Tree(s): OG0000449_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YLR044C
Cluster HCCA: Cluster_8

Target Alias Description ECC score Gene Family Method Actions
AFR97558 No alias pyruvate decarboxylase;Thiamine pyrophosphate enzyme,... 0.04 OF
AOA68293 No alias Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain 0.16 OF
CBF76546 No alias Pyruvate decarboxylase 0.03 OF
EAL84191 No alias pyruvate decarboxylase, putative 0.03 OF
ESU16466 No alias pyruvate decarboxylase 0.07 OF
KHC76728 No alias pyruvate decarboxylase;"Thiamine pyrophosphate enzyme,... 0.12 OF

Type GO Term Name Evidence Source
MF GO:0000287 magnesium ion binding IEA Interproscan
MF GO:0003824 catalytic activity IEA Interproscan
MF GO:0030976 thiamine pyrophosphate binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR012000 Thiamin_PyroP_enz_cen_dom 201 324
IPR011766 TPP_enzyme-bd_C 401 505
IPR012001 Thiamin_PyroP_enz_TPP-bd_dom 5 177
No external refs found!